 | Kyle MacLachlan Paul Atreides |
 | Francesca Annis Lady Jessica |
 | Patrick Stewart Gurney Halleck |
 | Linda Hunt Shadout Mapes |
 | José Ferrer Padisha Emperor Shaddam IV |
 | Freddie Jones Thufir Hawat |
 | Brad Dourif Piter De Vries |
 | Richard Jordan Duncan Idaho |
 | Virginia Madsen Princess Irulan |
 | Silvana Mangano Reverend Mother Ramallo |
 | Everett McGill Stilgar |
 | Sting Feyd Rautha |
 | Kenneth McMillan Baron Vladimir Harkonnen |
 | Jack Nance Nefud |
 | Siân Phillips Reverend Mother Gaius Helen Mohiam |
 | Jürgen Prochnow Duke Leto Atreides |
 | Leonardo Cimino The Baron's Doctor |
 | Paul L. Smith The Beast Rabban |
 | Dean Stockwell Doctor Wellington Yueh |
 | Max von Sydow Doctor Kynes |
 | Alicia Witt Alia |
 | Sean Young Chani |
 | Danny Corkill Orlop |
 | Honorato Magaloni Otheym |
 | Judd Omen Jamis |
 | Molly Wryn Harah |
 | Angélica Aragón Bene Gesserit Sister (uncredited) |
| Thomas Ebert House Atreides Guard (uncredited) |
 | Humberto Elizondo Czigo (uncredited) |
 | Ricardo Hill (uncredited) |
 | Ernesto Laguardia Harkonnen's Victim (uncredited) |
 | David Lynch Spice Miner (uncredited) |
 | Ramón Menéndez Kinet (uncredited) |
 | Ana Ofelia Murguía Palace Maid (uncredited) |
 | Claudia Ramírez Fremen Girl (uncredited) |
| Julieta Rosen Palace Maid (uncredited) |
| John Sabol Fedaykin Fighter (uncredited) |
 | Margarita Sanz Lady Jessica's Maid (uncredited) |
 | Jacqueline Voltaire (uncredited) |
| José Luis García Mainou (uncredited) |
| Directing | |
| David Lynch | Director |
Writing | |
| Frank Herbert | Novel |
| David Lynch | Screenplay |
Production | |
| Dino De Laurentiis | Executive Producer |
| Raffaella De Laurentiis | Producer |
Camera | |
| Freddie Francis | Director of Photography |
Editing | |
| Antony Gibbs | Editor |
Production | |
| Jane Jenkins | Casting |
Art | |
| Anthony Masters | Production Design |
| Benjamín Fernández | Art Direction |
| Giorgio Desideri | Set Decoration |
| Jorge Sainz | Set Decoration |
Costume & Make-Up | |
| Bob Ringwood | Costume Design |
Crew | |
| Kit West | Special Effects |
Visual Effects | |
| Carlo Rambaldi | Creature Design |
| Albert Whitlock | Additional Visual Effects |
Costume & Make-Up | |
| Mirella De Rossi | Hairstylist |
| Luigi Rocchetti | Makeup Artist |
| Mario Scutti | Makeup Artist |
| Mara Rossi | Wigmaker |
Art | |
| José María Alarcón | Assistant Art Director |
| Raul Paton Garcia | Assistant Art Director |
| Kevin Phipps | Assistant Art Director |
Crew | |
| Graham Sumner | Property Master |
Art | |
| Rafael Ablanque | Sculptor |
| Giulio Tamassy | Sculptor |
Sound | |
| Donald Flick | Foley |
| Jerry Ross | Foley |
| Alan Splet | Sound Designer |
| Leslie Shatz | Sound Editor |
| Teresa Eckton | Sound Editor |
| Steve Maslow | Sound Re-Recording Mixer |
| Kevin O'Connell | Sound Re-Recording Mixer |
| Bill Varney | Sound Re-Recording Mixer |
Crew | |
| Charles L. Finance | Special Effects Coordinator |
| Richard Humphreys | Stunt Coordinator |
Camera | |
| Chic Anstiss | Camera Operator |
| Gordon Hayman | Camera Operator |
| Ken Worringham | Camera Operator |
| George Whitear | Still Photographer |
Sound | |
| George Brand | Music Editor |
Directing | |
| Yvonne Axeworthy | Script Supervisor |
Crew | |
| Margaret Anderson | Dialect Coach |
Production | |
| José López Rodero | Associate Producer |
Crew | |
| Etsuko Egawa | Makeup Effects |
Costume & Make-Up | |
| Giannetto De Rossi | Makeup Artist |
Art | |
| Frank Silva | Set Dresser |
Lighting | |
| Maria Schiavone | Gaffer |
Art | |
| Pier Luigi Basile | Supervising Art Director |
Costume & Make-Up | |
| Etsuko Egawa | Special Effects Makeup Artist |
Directing | |
| José López Rodero | First Assistant Director |
Costume & Make-Up | |
| Mirella De Rossi | Key Hairdresser |
Crew | |
| Dickey Beer | Stunts |
| Wayne Michaels | Stunts |
| Scott Wilder | Stunts |
| Wendy Leech | Stunts |
| Vic Armstrong | Stunts |
Production | |
| Dino De Laurentiis | Producer |
Sound | |
| Brian Eno | Original Music Composer |
Crew | |
| Henry Kingi | Stunts |
| Tony Brubaker | Stunts |
Camera | |
| Frederick Elmes | Second Unit Director of Photography |
Art | |
| Peter Childs | Assistant Art Director |
Crew | |
| Kiyoshi Yamasaki | Fight Choreographer |
Art | |
| Ron Miller | Conceptual Illustrator |
Visual Effects | |
| Richard Malzahn | VFX Artist |
Art | |
| Richard Malzahn | Storyboard Artist |
Visual Effects | |
| Brian Smithies | Modelling Supervisor |
Sound | |
| David Paich | Original Music Composer |
| Jeff Porcaro | Original Music Composer |
| Mike Porcaro | Original Music Composer |
| Steve Porcaro | Original Music Composer |
| Marty Paich | Original Music Composer |
| Steve Lukather | Original Music Composer |
| Daniel Lanois | Original Music Composer |
| Roger Eno | Original Music Composer |
| James Newton Howard | Original Music Composer |
| TOTO | Music |
Crew | |
| Billy Bryan | Special Effects Technician |
